聚锑酸用于<sup>90</sup>Y发生器制备的可行性研究

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聚锑酸用于⁹⁰Y发生器制备的可行性研究

1. Chengdu YUNKE Pharmaceutical Co, LTD, Chengdu, 610041, China;
2. Chengdu Radiopharmaceutical Engineering Technology Research Center, Chengdu, 610041, China

摘要: 聚锑酸(PAA)在0.1 mol/L硝酸溶液中对Sr和Y的吸附容量分别为16.25 mg/g和42.1μg/g。不同浓度硝酸溶液不能将Sr和Y分离,二乙基三胺五乙酸(DTPA)和乙二胺四乙酸(EDTA)溶液可以洗脱Y而不能洗脱Sr。采用0.02 mol/L的EDTA为洗脱剂,Y的回收率能达到72%,但造成PAA交换剂不稳定。80℃下20 mL 0.12 mol/L的DTPA溶液可以洗脱86.2%的Y。研究结果表明,PAA有望制备成90Y发生器,但是发生器体系必须进行合理的设计以满足90Y发生器的要求。
- 聚锑酸 /
- Sr /
- Y /
- ⁹⁰Y发生器
Abstract: The adsorption capacity for Sr and Y with Polyantimonic Acid（PAA） in 0.1mol/L nitric acid solution was 16.25 mg/mL and 42.1 μg/g respectively. Sr and Y can’t be separated with nitric acid solution of different concentration. More than 72% of Y can be eluted with 100 mL 0.02 mol/L EDTA as elution, but PAA was unstable in EDTA solution. 86.2% of Y can be desorbed with 20 mL 0.12mol/L DTPA at the temperature is 80 ℃. The results indicated that PAA may be used for 90Y generator preparation, but system of generator should be rational designed to meet requires of 90Y generator.
- Polyantimonic acid /
- Strontium /
- Yttrium /
- 90Y generator