Abstract: Based on the reality of a State Key Laboratory,the paper studies the enviroment of science and technology information resources guarantee and the changes of user behavior under modern scientifical research environment,sums up misunderstandings that scientific and technolgical departments should avoided and provides a new pattern of information resources guarantee.At the same time,it discusses the sustainable development of science and technology information resources construction and puts forward the implenentation patterns of the core competencies of information department and knowledge services.