Abstract: Experimental study on creep/fatigue interaction of 316SS has been carried out.Three types of creep/fatigue interaction tests have been taken into consideration in the experiments,which include traditional creep/fatigue interaction subjected to cycling load with hold time and also creep/fatigue interaction by decoupling creep and fatigue loads.Based on the experimental data,the different types of creep/fatigue interaction have been compared and discussed.Total damage from creep and fatigue is evaluated according to linear life fraction rule.Test results show that in respect of specimen life,pre-fatigue/creep interaction is the worst,pre-creep/fatigue interaction is the best,and creep/fatigue interaction with hold time is in between.Fractograph（SEM） of the specimen is used to explain the test results.