Abstract: In the production and use of radioactive fuel process, it is an important process to measure the burn-up level for fuel element in accurate and efficient way. At present, the automatic operation of burn-up measurement of plate-type fuel element is unimplemented, and it applies only to single-point measurement.According to the structure of plate-type fuel element and the measurement requirements, the design of a new system which the interactive measurement point planning, motion control system, the gamma-ray energy spectrometer control, data processing and result visualization were integrated. It can realize multi-point,segmentation, automatic, nondestructive burn-up measurement of plate-type fuel element. The operation results show that the system is with high reliability, and can improve the efficiency and accuracy of measurement, thus to reduce the workload of the users.