Abstract: ASME（American Society of Mechanical Engineers） OM-S / G-2000 Part 3 of insufficient operational guidelines exists defects, while the vibration measurements for nuclear-class pipes in domestic nuclear power plants refer this guideline, with similar test method, which can not fully and accurately predict the pipeline vibration maximum points. In this paper, taking a nuclear power plant during the commissioning of nuclear grade pipe vibration measurements as an example, the screening of test objects, selection of the critical equipment or components, selection of measurement point, field test and vibration evaluation are discussed, and the recommendation for improvement is proposed. Finally, taking some pipe vibration of someone nuclear power plant EAS system（containment spray system） as the research object, we analyze the method of measurement, calculation and evaluation of vibration limits.