Abstract: The relevant seismic fortification standards and requirements on both domestic and international nuclear fuel cycle facilities were briefly described in this paper.Taking the facility potential risk as the starting point of seismic fortification and fully considering the specific characteristics of nuclear fuel cycle facilities extensively,this paper discussed the key factors of seismic fortification.In addition,taking the seismic fortification practice in domestic nuclear facilities into account,the requirements and suggestions on typical nuclear fuel cycle facility were made,and the international relevant seismic fortification requirements were compared for the purpose of reaching a clear unified agreement on seismic fortification criterion,to offer suggestions for nuclear fuel cycle facility design and evaluation to some extent.