Abstract: This paper analyzes the key impacts that DCS system brings to the nuclear power plant operations with real cases, and based on these analyses, it proposes the requirement that non-safety DCS systems could also apply Single-Failure criteria in nuclear power plants. In the meantime, this paper proposes the idea of dynamic management to the Single Point Vulnerability components respectively to different operation conditions and plant status of nuclear power plants. In addition, it discusses the importance of the DCS online maintenance capacity. The studies in this paper is helpful for the DCS operation, maintenance and management of a nuclear power plant.