Abstract: Prognostics and Health Management（PHM） system is able to improve the safety of nuclear power plants and reduce maintenance costs.Prognostics and Health Management system includes five modules:data collection and processing,condition monitoring,fault diagnosis,life prediction and health management.Dedicated monitoring methods and prediction algorithms with appropriate prognostics performance metrics should be applied.This paper presents the suitable development route of PHM system in nuclear power plants in China.Maintenance standards and regulations should be formulated and fault database should be built which provides a good basis for PHM system to be widely used in nuclear power plants in China.