Abstract: The full-range simulator in Tianwan nuclear power plant is mainly used for the training and authorization of the operators in the master control room. Since it is an important tool and means for operator training, its consistency with the main unit and its availability shall be guaranteed. In order to that the simulator management system meets the requirement of the standards in the national energy industry, and the requirement of digitalized comprehensive maintenance and management, Nuclear Power Institute of China designed and integrated the multi-unit simulator management system. The system ensures that the simulator’s maintenance and management satisfies the industrial standards, and the system enhances the simulator management in nuclear power station. Currently, the system has been successfully applied in the simulators in units 1/2 of Tianwan Nuclear Power Station. It can be applied directly in the simulators in units 3/4 and units 5/6 in the future. At the same time, the system can applied to other NPPs in service and to be built by a small amount of customized development.