Water is used as the lubricant for the axletree by Tianwan nuclear power plant. The heat generation by rate is on the high side, and serious abrasion is found on the axletree. The paper studies the characteristics of the flow and pressure in the axletree room by computed fluid dynamics(CFD) method for the abrasion of the axletree. Analysis shows that the reason for the abrasion and high heat generation rate of the axletree is cavitation; and the cavitation is caused by the flow acceleration effect of local area.