Under seismic or LOCA condition,dynamic collision and impact will occur between the the adjacent fuel assemblies located in the reactor core.The object of safety analysis of fuel assembly for combined seismic and loss-of-coolant accident is to evaluate the performance of fuel assembly under limiting condition,and to demonstrate the satisfaction of related design criteria.The safety analysis is based on several fuel assembly models,including the detailed model,lumped mass model and impact model.According to the analysis results for a certain plant,the fuel assembly in this plant can meet all the design criteria related to fuel assembly performance under combined seismic and LOCA condition.The research of safety analysis method for fuel assembly under seismic and LOCA condition can provide theoretic guidance for the setup of fuel assembly safety evaluation system.