Mesh separators are widely used in industry. Based on the dynamic process of droplet impact on the mesh in this paper, the CLSVOF method is used to solve the problem of single droplet impact on the dry flat wire mesh. After reasonable simplification, a two-dimensional mathematical model of the single droplet impacting mesh surface is established and analyzed. The effects of droplet impact angle and impact position on the behavior of droplet impacting were studied. The numerical results show that the droplets impacting on the dry mesh are divided into two processes: spreading and splashing. The smaller the impact angle, the bigger the front spreading radius, and the smaller the back spreading radius, the larger the volume of the daughter droplets; the closer the impact point is to the end of the mesh, the more likely to produce daughter droplets, the more the total volume of daughter droplets.