Abstract: The risk-informed regulation is a modern type of NPP safety management mode using both deterministic and probabilistic approaches.It is necessary to entirely and systematically study the associated regulations,standards and practices in order to promote the developments of risk-informed regulations in China.This paper introduces the risk-informed regulation,gives out the basic principles,method and acceptance risk criteria of risk-informed decision-making,discusses the PSA requirements for risk-informed decision-making and makes some suggestions about the application of risk-informed regulations in Chinese NPP.