Abstract: Reasons why the extrapolated critical curve obtained by lifting control rods is cambered during the physical start-up of a reactor are analyzed. Spatial flux deformation factor is introduced, and a new method, by which influences of spatial effect in the reactor are avoided additionally, is proposed based on what is achieved by removing source neutrons. The new method is employed to a real example. Comparing the new results with those of real physical start-up and achieved only by removing source neutrons, it is shown that the new method avoids cambering phenomenon of the extrapolated curve much better, and obtains more precise critical position of control rods, so the reactor will reach the criticality more safely.