Abstract: In order to improve the safety,economy and reliability of the operation of a nuclear power plant（NPP）,a novel integrated management method is proposed based on the "integration" concept of the computer and contemporary integrated manufacture systems（CIMS） in this paper.The design of integrated management system for NPP is studied.In the design of this system,information integration method based on the database and product data management（PDM） technology is adopted.In order to design an integrated management system satisfying the needs of NPP management,all activities of NPP are divided into different categories according to its characteristics.There are subsystems under the general management system to conduct the management work of different catego-ries.All subsystems are interrelated in the environment of CIMS,but relatively independent.The application of CIMS to NPP provides a new way for scientific management of NPP,and makes the best of human,material and information resources.