Abstract: Considering the disadvantages of the steel pressure vessels in modular high temperature gas-cooled reactor （MHTR）, such as high cost and difficulties in manufacture and transportation, the technical feasibility study is performed for the pre-stressed concrete pressure vessel （PCPV） in MHTR. The paper briefly presents the development status and technical characteristics of PCPV, analyzes and studies the technical crux and feasibility of PCPV as the primary system pressure boundary components of MHTR. The preliminary design of PCPV is proposed for MHTR. The analysis proves that PCPV utilized in MHTR is feasible, which could not only solve the technical crux, such as mechanics problems and decay heat removal in the multi-cavity of PCPV, but also improve the s economic competition and safety of MHTR.