Abstract: The high cycle fatigue behavior of titanium alloy Ti-4Al-2V rods at room temperature was evaluated.The common high cycle fatigue（HCF） tests with group specimen and the up-and-down tests were performed under bending and rotating loadings at room temperature in air environment.The experimental data were analyzed and the S-N curve and P-S-N curve were plotted,and the fracture morphology is analyzed by SEM.The results show that Ti-4Al-2V rods have good resistance to high cycle fatigue and the value ofσ_{-1（10）⁷} is about the same with that of the corresponding equation.The fracture morphology of Ti-4Al-2V specimen after fatigue failure presents typical characteristics with three areas of fatigue crack initiation,growth and rupture.