Abstract: The supply of electronic instrumentation and controlling（I＆C） equipments in Daya Bay Nuclear Power Station depends on importation up to now,however,reliable supply of spare parts is presently threatened by many factors.Consequently,Daya Bay Nuclear Power Station tries to localize these equipments.According to a survey,China has possessed the ability to undertake the research,development and production of the I＆C system in nuclear power independently.We propose that localization should firstly starts with the production of replacement board and parts for analogical I＆C system,gradually leads to the substitution of system cabinet units,and finally realize the independent research,development and production of advanced digital main control system.A series of prominent problems of producing nuclear grade I＆C equipments are focused on the designing,manufacturing,testing and reliability evaluation.In this paper,technical procedures,regulations,standards and management experiences related to the localization of nu-clear power electrical and I＆C are introduced.