Abstract: Interactive of human error factors in NPP operation events were introduced,and 645 WANO operation event reports from 1999 to 2008 were analyzed,among which 432 were found relative to human errors.After classifying these errors with the Root Causes or Causal Factors,and then applying SPSS for correlation analysis,we concluded:（1） Personnel work practices are restricted by many factors.Forming a good personnel work practices is a systematic work which need supports in many aspects.（2）Verbal communications,personnel work practices,man-machine interface and written procedures and documents play great roles.They are four interactional factors which often come in bundle.If some improvements need to be made on one of them,synchronous measures are also necessary for the others.（3） Management direction and decision process,which are related to management,have a significant interaction with personnel factors.