Abstract: Fluid induced vibration of the angle stop valve was obvious which brings some difficulties for controlling the vibration and the noise in the cooling water system of some nuclear devices. For reducing the vibration, the fluid induced vibration characteristics of both the angle stop valve and oblique stop valve are calculated and compared. Results show that for both valves, the pressure fluctuation after the valves are larger than that before the valves. However, the intensity of vortex, the force of valve core and the amplitude of pressure fluctuation for the oblique stop valve are less than that of the angel stop valve, so the fluid induced vibration characteristics of the oblique stop valve is better than that of the angle stop valve.