The finite element model of steam generator secondary separator was developed, and the analysis of the structural vibration characteristics and the aerodynamic noise of the steam dryer was completed. The frail plate part of steam dryer was found based on the vibration study. In the aerodynamic noise section, the maximum static pressure and pressure power spectral density(PSD) were included. Structural strength and fatigue characteristics were studied under the aerodynamic loads. The results demonstrated that the main frail plates are the vertical partition plate and perforated plate at the steam dryer. The maximum stress intensity appears at the perforated plate. But it is less than the limit value, and meets the requirement of RCC-M specifications.