Big errors will occur in the modeling by multimode methodology when the available core physical parameter sets are insufficient. In this paper, the fuzzy logic membership function is introduced to figure out the values of these parameters on any point of lifetime through limited several sets of values, and thus to obtain the neutron dynamics equations on any point of lifetime. In order to overcome the effect ofsubjectivity in the membership function selection on the parameter calculation, quadratic optimization is carried out to the membership function by genetic algorithm, to result in a more accurate neutron kinetics equation on any point of lifetime.