This paper puts forward a new method measuring the activity of neutron-activation-foil using 4πβ-γ coincidence equipment without making thin film source.By changing the voltage of photomultiplier tube,keeping the same efficiency of the γ detector in detection of γ photon and X ray of K shell,we can obtain the activity of neutron-activation-foil,without using efficiency extrapolation method.Theory analysis indicates that the method is feasible.