Abstract: Sodium-cooled fast breeder reactor（SFR）is recognized as one of the most mature and most promising commercial fast reactors.However,due to the aspects of materials,coolant safety and economics,SFR in China is still in the operation stage of experimental reactor at present.Due to the lack of SFR’s regulations,standards,technology and experience of the safety regulation,the regulatory work is facing great challenges.In this paper,SFR is compared with PWR.The characteristics of SFR and safety regulatory are combined to propose 15 items of major regulatory concerns,such as core,system and equipment,and a series of related suggestions is given.