Based on the critical/subcritical point kinetics model, the fuel pin heat transfer model, and the auxiliary thermal hydraulic models such as the heat exchanger model and the porous media model, a multi-physical coupling code CFD/PF was developed by means of the explicit iteration method, dynamic link library technique (DLL) and user-defined functions (UDF) of FLUENT. The CFD/PF was used to carry out the simulation of SNCLFR-100 unprotected transient of over power (UTOP) of a small natural circulation LBE cooled fast reactor, and the code-to-code comparison analysis was conducted with the renowned multi-physical coupling code SIMMER-III. The results indicated that the CFD/PF simulation results are in a good agreement with SIMMER-III calculation results, and the multi-physical analysis method and code development have been achieved initial success, which can be used to analyze the complex three-dimensional flow and heat transfer phenomena in pool-type fast reactors.